Fasting tips

According to the Centers for Disease Control, there are more than 160,000 Americans who have an eating disorder. This is an unfortunate fact. In fact, both men and women who suffer from eating disorders are at much higher risk of developing diabetes.
 
The science and logic behind it is pretty straightforward: people with eating disorders overeat to excess, reducing their calorie intake too dramatically, which can lead to insulin resistance and diabetes. And that’s a huge problem because diabetes is ultimately a metabolic disease that causes your body to become insulin resistant and obese.
 
We have a lot of questions about why this happens but no easy answer — until now. After conducting numerous experiments with fasting (or low-energy-density diets) in both humans and mice we have discovered a mechanism that may explain why people with eating disorders become insulin resistant: the loss of leptin (a hormone associated with feelings of satiety) caused by fasting reduces the amount of leptin circulating in your bloodstream which results in further reduced leptin production, leading to further glucose intolerance and obesity (in other words, it’s like starving yourself but less painful).
 
 
However, while this explanation may fit together very neatly we need more experiments … not just to confirm our hypothesis but to bring it into the mainstream. We want our test subjects as many as possible; we want them to be able to fast without any side effects; we want them to be healthy before they start fasting; we want them able to do so for weeks or even months before embarking on such a long fast; and finally most importantly, we want them able to fast for several days at once (e.g., three days on one day off).

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